Cell-Intrinsic and Extrinsic Effects of Galectin-1 and Galectin-3 in B-Cell Precursor Acute Lymphoblastic Leukemia
N. Heisterkamp, E. j. Joo, L. Yang, J. Groffen, F. Fei
This study shows Galectin-1 and Galectin-3 promote BCP-ALL cell growth and survival through intrinsic and extrinsic mechanisms, and their inhibition increases chemotherapy sensitivity.
bioRxiv · Sep 22, 2021 · PreprintCancer Biology