PIKfyve is required for phagosomal Rab7 acquisition and the delivery and fusion of early macropinosomes to phagosomes
J. H. Vines, C. M. Buckley, J. S. King
This study shows that PIKfyve is essential for phagosomes to acquire Rab7 via fusion with PI(3,5)P2-positive macropinosomes, enabling efficient lysosomal component delivery.
bioRxiv · Sep 19, 2022 · PreprintCell Biology