Author

J. S. King

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 6 Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 6 Approach:experimental assay· 6 Research Focus:cell type annotation· 4 Research Focus:development & morphogenesis· 3 Research Focus:host-pathogen & immune response· 3 Assay:imaging· 3 Organism:Drosophila· 2 Approach:microscopy & imaging analysis· 2

Frequent Co-Authors

B. A. Phillips· 2 shared C. M. Buckley· 2 shared G. P. Starling· 2 shared T. Soldati· 2 shared A. Bernut· 1 shared A. Gueho· 1 shared A. J. Cadby· 1 shared A. J. Parnell· 1 shared

Activity by Year

2018-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCell Biology

B. A. Phillips

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Pulses of Class I PI3kinase activity identify the release and recapture of prey from neutrophil phagosomes

C. F. Muir, C. C. Reyes-Aldasoro, F. Ellett, T. Prajsnar, Y. X. Ho, A. Bernut, C. A. Loynes, S. Elworthy, K. A. Bowden, A. J. Cadby, L. Prince, J. S. King, A. M. Condliffe, S. Renshaw

The paper identifies pulsatile Class I PI3K activity on neutrophil phagosomes during bacterial infection, suggesting phagosomes reopen and reclose to release or restart digestion.

bioRxiv · Feb 29, 2024 · PreprintCell Biology

Wnt-associated adult stem cell marker Lgr6 is required for osteogenesis and fracture healing

L. Doherty, M. Wan, A. Peterson, D. W. Youngstrom, J. S. King, I. Kalajzic, K. D. Hankenson, A. Sanjay

This study shows that Lgr6 is essential for osteogenesis and fracture healing by maintaining bone volume and promoting stem cell activity in mice.

bioRxiv · Dec 9, 2022Cell Biology

The formation and closure of macropinocytic cups in a model system

J. Lutton, H. Coker, P. Paschke, C. Munn, J. S. King, R. Kay, T. Bretschneider

This study investigates macropinocytic cup formation and closure in Dictyostelium using lattice light-sheet microscopy, identifying two closure mechanisms and proposing a stalled wave hypothesis.

bioRxiv · Oct 7, 2022Cell Biology

PIKfyve is required for phagosomal Rab7 acquisition and the delivery and fusion of early macropinosomes to phagosomes

J. H. Vines, C. M. Buckley, J. S. King

This study shows that PIKfyve is essential for phagosomes to acquire Rab7 via fusion with PI(3,5)P2-positive macropinosomes, enabling efficient lysosomal component delivery.

bioRxiv · Sep 19, 2022 · PreprintCell Biology

Katnip is required to maintain microtubule function and lysosomal delivery to autophagosomes and phagosomes

G. P. Starling, B. A. Phillips, S. Ganesh, J. S. King

The paper shows Katnip maintains microtubule function and lysosomal delivery to autophagosomes and phagosomes in Dictyostelium discoideum.

bioRxiv · Feb 22, 2022Cell Biology

Environmental interactions with amoebae as drivers of bacterial-fungal endosymbiosis and pathogenicity

H. Itabangi, P. Sephton-Clark, X. Zhou, G. P. Starling, Z. Mahamoud, I. Insua, M. Probert, J. Correia, P. Moynihan, Y. Gu, T. Gebremariam, A. S. Ibrahim, G. D. Brown, J. S. King, E. R. Ballou, K. Voelz

The paper identifies a bacterial endosymbiont in Rhizopus microsporus that enhances fungal virulence by suppressing amoeba predation and macrophage clearance.

bioRxiv · Dec 17, 2020 · PreprintMicrobiology

Co-ordinated Ras and Rac activity shapes macropinocytic cups and enables phagocytosis of geometrically diverse bacteria

C. M. Buckley, H. Pots, A. Gueho, B. A. Phillips, B. Gilsbach, D. Traynor, A. Nikolaev, T. Soldati, A. J. Parnell, A. Kortholt, J. S. King

This study shows that RGBARG coordinates Ras and Rac activity to shape macropinocytic cups and enable phagocytosis of geometrically diverse bacteria in Dictyostelium discoideum.

bioRxiv · Oct 17, 2019Cell Biology

ESCRT and autophagy cooperate to repair ESX-1-dependent damage to the Mycobacterium-containing vacuole

A. T. Lopez-Jimenez, E. Cardenal Munoz, F. Leuba, L. Gerstenmaier, M. Hagedorn, J. S. King, T. Soldati

The paper shows that ESCRT and autophagy work together to repair damage to the Mycobacterium-containing vacuole caused by ESX-1, preventing bacterial escape.

bioRxiv · May 30, 2018Microbiology