Author

J. Harju

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:chromatin & epigenetic regulation· 3 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Approach:experimental assay· 1 Assay:Hi-C· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

C. P. Broedersz· 3 shared C. F. Nielsen· 1 shared C. M. Bruinsma· 1 shared E. J. Peterman· 1 shared E. M. Chameau· 1 shared G. J. Wuite· 1 shared H. Witt· 1 shared I. D. Hickson· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiophysics

C. P. Broedersz

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Ion-mediated condensation controls the mechanics of mitotic chromosomes

H. Witt, J. Harju, E. M. Chameau, C. M. Bruinsma, T. V. Clement, C. F. Nielsen, I. D. Hickson, E. J. Peterman, C. P. Broedersz, G. J. Wuite

The paper shows that ion-mediated condensation controls the mechanical properties of mitotic chromosomes through polymer-like behavior and chromatin loop interactions.

Nature Materials · Sep 16, 2024Peer-reviewedBiophysics

Loop-extruders alter bacterial chromosome topology to direct entropic forces for segregation

J. Harju, M. C. F. van Teeseling, C. P. Broedersz

The paper develops a biophysical model showing loop-extruders enhance entropic forces for bacterial chromosome segregation during replication.

bioRxiv · Jun 30, 2023 · PreprintBiophysics

Physical models for chromosome organization to predict multi-contact statistics

J. Harju, J. J. B. Messelink, C. P. Broedersz

The paper develops three predictors of multi-contact frequencies using physical models and applies them to experimental data, finding that loop-extrusion explains observed three-point contacts.

bioRxiv · May 17, 2022 · PreprintBiophysics