Long lifetime and selective accumulation of the A-type lamins accounts for the tissue specificity of Hutchinson-Gilford progeria syndrome
J. Hasper, K. Welle, K. Swovick, J. Hryhorenko, S. Ghaemmaghami, A. Buchwalter
This study shows that the long lifetime and selective accumulation of A-type lamins in specific tissues explain the tissue specificity of Hutchinson-Gilford progeria syndrome.
bioRxiv · Feb 4, 2023 · PreprintCell Biology