Author

K. Welle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

S. Ghaemmaghami· 4 shared K. Swovick· 2 shared A. Buchwalter· 1 shared A. Mohan· 1 shared C. Yan· 1 shared E. Small· 1 shared F. Jiang· 1 shared J. Hasper· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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4 shared papersBiochemistry

S. Ghaemmaghami

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4 papers

Recent·Most cited

Methionine Alkylation as an Approach to Quantify Methionine Oxidation Using Mass Spectrometry

M. Hoare, R. Tan, K. Welle, K. Swovick, J. R. Hryhorenko, S. Ghaemmaghami

This paper introduces MObBa, a mass spectrometry method to quantify methionine oxidation by alkylating unoxidized methionines, enabling accurate measurement of oxidation levels in peptides and proteomes.

bioRxiv · Sep 21, 2023Biochemistry

Long lifetime and selective accumulation of the A-type lamins accounts for the tissue specificity of Hutchinson-Gilford progeria syndrome

J. Hasper, K. Welle, K. Swovick, J. Hryhorenko, S. Ghaemmaghami, A. Buchwalter

This study shows that the long lifetime and selective accumulation of A-type lamins in specific tissues explain the tissue specificity of Hutchinson-Gilford progeria syndrome.

bioRxiv · Feb 4, 2023 · PreprintCell Biology

MicroRNA-574 Regulates FAM210A Expression and Influences Pathological Cardiac Remodeling

J. Wu, K. C. V. Subbaiah, F. Jiang, O. Hedaya, A. Mohan, T. Yang, K. Welle, S. Ghaemmaghami, W. H. W. Tang, E. Small, C. Yan, P. Yao

This study identifies miR-574 as a regulator of FAM210A, which influences mitochondrial protein expression and cardiac remodeling in heart failure.

bioRxiv · Jan 9, 2020Pathology

Potential Mechanisms Linking SIRT Activity And Hypoxic 2-Hydroxyglutarate Generation: No Role For Direct Enzyme (De)acetylation

S. Nadtochiy, Y. T. Wang, J. Zhang, K. Nehrke, X. Schafer, K. Welle, S. Ghaemmaghami, J. Munger, P. Brookes

This study investigates whether sirtuin-mediated acetylation regulates 2-HG production by metabolic enzymes, finding no direct link between enzyme acetylation and 2-HG generation.

bioRxiv · May 24, 2017Biochemistry