Non-monotonic fibril surface occlusion by GFP tags from coarse-grained molecular simulations
J. C. Shillcock, J. Hastings, N. Riguet, H. Lashuel
This study shows that GFP tags on amyloid fibrils create a non-monotonic sieve effect, altering their interactome and growth dynamics through coarse-grained simulations.
bioRxiv · Oct 21, 2021Biophysics