Disease associated mutations in tau encode for changes in aggregate structure conformation
K. Sun, T. Patel, S.-G. Kang, A. Yarahmady, O. Julien, J. Heras, S.-A. Mok
This study shows that disease-associated tau mutations alter the structure of tau aggregates, revealing new insights into their pathological mechanisms.
bioRxiv · Apr 24, 2023Biochemistry