Author

O. Julien

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Organism:virus· 1

Frequent Co-Authors

A. P. Bhavsar· 1 shared A. Yarahmady· 1 shared B. Bai· 1 shared B. E. Dubrule· 1 shared C. Delyea· 1 shared E. Arutyunova· 1 shared E. Moussa· 1 shared H. S. Young· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperMicrobiology

A. P. Bhavsar

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Disease associated mutations in tau encode for changes in aggregate structure conformation

K. Sun, T. Patel, S.-G. Kang, A. Yarahmady, O. Julien, J. Heras, S.-A. Mok

This study shows that disease-associated tau mutations alter the structure of tau aggregates, revealing new insights into their pathological mechanisms.

bioRxiv · Apr 24, 2023Biochemistry

SARS-CoV-2 Mpro protease variants of concern display altered viral and host target processing but retain potency towards antivirals

S. A. Chen, E. Arutyunova, J. Lu, M. B. Khan, W. Rut, M. Zmudzinski, S. Shahbaz, J. Iyyathurai, E. Moussa, Z. Turner, B. Bai, T. Lamer, J. A. Nieman, J. C. Vederas, O. Julien, , M. J. Lemieux

The paper examines how SARS-CoV-2 Mpro variants affect viral and host protein processing but maintain antiviral potency.

bioRxiv · Jan 28, 2023 · PreprintBiochemistry

NOD1 is super-activated through spatially-selective ubiquitination by the Salmonella effector SspH2

C. Delyea, S. Y. Luo, B. E. Dubrule, O. Julien, A. P. Bhavsar

This paper identifies SspH2 as an E3 ubiquitin ligase that super-activates NOD1 and NOD2 through spatially-selective ubiquitination, enhancing pro-inflammatory cytokine secretion via the NF-κB pathway.

bioRxiv · Oct 8, 2021 · PreprintMicrobiology