Author

J. Hesselberth

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

T. Morrison· 2 shared A. L. Franklin· 1 shared A. Macfadden· 1 shared A. Martin· 1 shared A. Uecker-Martin· 1 shared B. A. J. Tamburini· 1 shared B. Davenport· 1 shared B. Tamburini· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersImmunology

T. Morrison

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A specific and portable gene expression program underlies antigen archiving by lymphatic endothelial cells

R. M. Sheridan, T. A. Doan, C. A. Lucas, T. S. Forward, A. Uecker-Martin, T. Morrison, J. Hesselberth, B. A. J. Tamburini

The paper identifies a unique transcriptional program in lymphatic endothelial cells that predicts antigen archiving capacity and validates it across datasets and in vivo.

bioRxiv · Apr 1, 2024 · PreprintImmunology

Chikungunya virus infection disrupts lymph node lymphatic endothelial cell composition and function via MARCO

C. Lucas, R. Sheridan, G. Reynoso, B. Davenport, M. McCarthy, A. Martin, J. Hesselberth, H. Hickman, B. Tamburini, T. Morrison

This study shows CHIKV infection disrupts lymph node lymphatic endothelial cell composition and function through MARCO interactions, leading to impaired antigen acquisition and increased inflammation.

JCI Insight · Jan 9, 2024Peer-reviewedImmunology

Engineering degradation-resistant messenger RNAs in yeast

A. L. Franklin, A. Macfadden, J. G. Kieft, J. Hesselberth, E. G. Chapman

This study shows that viral RNA structures can protect mRNA from degradation in yeast, increasing protein expression by 30-fold.

bioRxiv · Jun 25, 2020 · PreprintBiochemistry