The aryl hydrocarbon receptor and interferon gamma generate antiviral states via transcriptional repression
P. D. Bieniasz, T. Kueck, E. Cassella, J. Holler, B. Kim
This study shows that AhR and IFN-gamma activation repress CDK1/2 and cyclins, reducing dNTP levels and inhibiting HIV-1 and HSV-1 replication.
bioRxiv · Jun 22, 2018Immunology