Vesicular stomatitis virus transcription is inhibited by TRIM69 in the interferon-induced antiviral state
T. Kueck, L.-M. Bloyet, E. Cassella, T. Zang, F. Schmidt, V. Brusic, G. Tekes, O. Pornillos, S. Whelan, P. D. Bieniasz
This study identifies TRIM69 as an IFN-induced antiviral factor that inhibits VSVIND replication by targeting its phosphoprotein P through a novel transcriptional inhibition mechanism.
bioRxiv · Jun 27, 2019Microbiology