Author

J. Hulleman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

B. Aredo· 1 shared B. Chen· 1 shared D. Woodard· 1 shared E. Nakahara· 1 shared H. Peng· 1 shared M. Renwick· 1 shared P. Ramadurgum· 1 shared R. Ufret-Vincenty· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperPhysiology

B. Aredo

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2 papers

Recent·Most cited

A simple secretion assay for assessing new and existing myocilin variants

J. Hulleman, E. Nakahara

The paper develops a Gaussia luciferase-based assay to assess MYOC variant secretion and compares it to western blotting, finding strong agreement for most variants.

bioRxiv · Oct 30, 2021Biochemistry

SUFFICIENT ACTIVITY OF THE UBIQUITIN PROTEASOME SYSTEM IN AGED MICE AND DURING RETINAL DEGENERATION SUPPORTS DHFR-BASED CONDITIONAL CONTROL OF PROTEIN ABUNDANCE IN THE RETINA

H. Peng, P. Ramadurgum, D. Woodard, S. Daniel, M. Renwick, B. Aredo, S. Datta, B. Chen, R. Ufret-Vincenty, J. Hulleman

This study evaluates the effectiveness of a DHFR-based system for conditional protein control in aged and retinal degeneration mouse models, showing successful degradation despite compromised UPS in some models.

bioRxiv · Apr 13, 2021Physiology