Author

E. Nakahara

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

J. D. Hulleman· 2 shared A. Abbas· 1 shared D. R. Woodard· 1 shared J. Hulleman· 1 shared L. A. Joachimiak· 1 shared S. Daniel· 1 shared S. M. DiCesare· 1 shared V. Mullapudi· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 13 mutual co-author links

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2 shared papersBiochemistry

J. D. Hulleman

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3 papers

Recent·Most cited

Development of a new DHFR-based destabilizing domain with enhanced basal turnover and applicability in mammalian systems

E. Nakahara, V. Mullapudi, L. A. Joachimiak, J. D. Hulleman

The paper develops a new destabilizing domain (C12) with reduced basal levels and improved dynamic range, demonstrating its utility in regulating stress-responsive proteins.

bioRxiv · Jun 21, 2022Biochemistry

A loss-of-function cysteine mutant in fibulin-3 (EFEMP1) forms aberrant extracellular disulfide-linked homodimers and alters extracellular matrix composition

D. R. Woodard, S. Daniel, E. Nakahara, A. Abbas, S. M. DiCesare, J. D. Hulleman

This study investigates how a cysteine mutation in fibulin-3 (C55R) disrupts its structure and function, leading to altered extracellular matrix composition and impaired ECM remodeling.

bioRxiv · Feb 25, 2022Biochemistry

A simple secretion assay for assessing new and existing myocilin variants

J. Hulleman, E. Nakahara

The paper develops a Gaussia luciferase-based assay to assess MYOC variant secretion and compares it to western blotting, finding strong agreement for most variants.

bioRxiv · Oct 30, 2021Biochemistry