Structural basis for APE1 processing DNA damage in the nucleosome
T. M. Weaver, N. M. Hoitsma, J. J. Spencer, L. Gakhar, N. J. Schnicker, B. D. Freudenthal
This study reveals how APE1 processes DNA damage in nucleosomes by bending DNA to access AP sites, with efficiency depending on site exposure.
bioRxiv · Mar 9, 2022Biochemistry