BRCA2 BRC missense variants disrupt RAD51-dependent DNA repair
J. Jimenez-Sainz, J. Mathew, G. Moore, S. Lahiri, J. Garbarino, J. P. Eder, E. Rothenberg, R. B. Jensen
This study evaluates three BRCA2 missense variants, showing two disrupt RAD51 binding and DNA repair, while the third is functional and benign.
bioRxiv · Sep 24, 2021Cancer Biology