Author

J. Mathew

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1

Frequent Co-Authors

A. Cox· 1 shared A. K. Bharti· 1 shared A. V. Rueda· 1 shared E. C. Unan· 1 shared E. J. Swayze· 1 shared E. Oki· 1 shared E. Rothenberg· 1 shared F. D'Alessio· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperImmunology

A. Cox

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Pseudomonas aeruginosa Elicits Sustained IL-1β Upregulation in Alveolar Macrophages from Lung Transplant Recipients

N. Britton, A. V. Rueda, S. A. Whiteside, J. Mathew, M. Kelley, S. Agbor-Enoh, J. McDyer, J. D. Christie, R. G. Collman, A. Cox, P. Shah, F. D'Alessio

This study shows that Pseudomonas aeruginosa and its dominant microbiota increase IL-1β production in alveolar macrophages from lung transplant recipients, which can be reduced by inflammasome inhibitors.

bioRxiv · Apr 26, 2022 · PreprintImmunology

BRCA2 BRC missense variants disrupt RAD51-dependent DNA repair

J. Jimenez-Sainz, J. Mathew, G. Moore, S. Lahiri, J. Garbarino, J. P. Eder, E. Rothenberg, R. B. Jensen

This study evaluates three BRCA2 missense variants, showing two disrupt RAD51 binding and DNA repair, while the third is functional and benign.

bioRxiv · Sep 24, 2021Cancer Biology

A Fully Implantable Wireless Bidirectional Neuromodulation System for Mice

J. Wright, J. Wong, J. Mathew, I. Mughrabi, N. Jayaprakash, T. Zanos, Y. Al Abed, S. Zanos, T. Datta-Chaudhuri

This paper presents a fully-implantable wireless neuromodulation system for mice capable of bidirectional signal exchange and long-term functionality.

bioRxiv · Jun 2, 2021Bioengineering

CTDSP1 inhibitor rabeprazole regulates DNA-PKcs dependent topoisomerase I degradation and irinotecan drug resistance in colorectal cancer

H. Matsuoka, K. Ando, E. J. Swayze, E. C. Unan, J. Mathew, Q. Hu, Y. Tsuda, Y. Nakashima, H. Saeki, E. Oki, A. K. Bharti, M. Mori

This study shows that rabeprazole inhibits CTDSP1, which promotes irinotecan resistance in colorectal cancer by enhancing DNA-PKcs-mediated topoisomerase I degradation.

bioRxiv · Jan 7, 2020Cancer Biology