Author

J. Koester

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Organism:mouse· 1 Organism:plant (other)· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. Chrachri· 1 shared A. Scarpa· 1 shared A. Taylor· 1 shared B. Horsthemke· 1 shared B. Sitek· 1 shared C. Brownlee· 1 shared C. Schroeder· 1 shared D. Behrens· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

A. Chrachri

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Epigenetic plasticity via adaptive DNA hypermethylation and clonal expansion underlie resistance to oncogenic pathway inhibition in pancreatic cancer

L. K. Godfrey, J. Forster, S.-T. Liffers, C. Schroeder, J. Koester, L. Henschel, K. U. Ludwig, M. Trajkovic-Arsic, D. Behrens, A. Scarpa, R. T. Lawlor, K. E. Witzke, B. Sitek, S. A. Johnsen, S. Rahmann, , J. T. Siveke

This study identifies adaptive DNA methylation changes and clonal expansion as mechanisms of resistance to MEKi in PDAC, showing reversibility upon drug withdrawal.

bioRxiv · May 20, 2022 · PreprintCancer Biology

A novel single-domain Na+-selective voltage-gated channel in photosynthetic eukaryotes

K. E. Helliwell, A. Chrachri, J. Koester, S. Wharam, A. Taylor, G. Wheeler, C. Brownlee

The paper identifies a novel class of Na+-selective single-domain voltage-gated channels in haptophyte algae, demonstrating rapid Na+-based signaling in photosynthetic eukaryotes.

bioRxiv · Apr 29, 2020Microbiology