Recombinant annexin A6 promotes membrane repair in a stem cell derived-cardiomyocyte model of dystrophic cardiomyopathy
D. E. Fullenkamp, A. B. Willis, J. L. Curtin, A. P. Amaral, S. I. Harris, P. W. Burridge, A. R. Demonbreun, E. M. McNally
The paper demonstrates that recombinant annexin A6 reduces membrane damage in DMD iPSC-CMs under mechanical stress, showing potential therapeutic efficacy for DMD-related cardiomyopathy.
bioRxiv · Mar 9, 2022 · PreprintBioengineering