Author

P. W. Burridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Bioengineering· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1

Frequent Co-Authors

A. L. George· 2 shared C. Epting· 2 shared C. J. Weddle· 2 shared H. Fonoudi· 2 shared J.-M. DeKeyser· 2 shared T. Magdy· 2 shared A. B. Willis· 1 shared A. K. Fetterman· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersPharmacology & Toxicology

A. L. George

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A Novel Transcription Factor Combination for Direct Reprogramming to a Spontaneously Contracting Human Cardiomyocyte-like State

M. R. Tejeda, H. Fonoudi, C. J. Weddle, J.-M. DeKeyser, B. Lenny, A. K. Fetterman, T. Magdy, Y. Sapkota, C. Epting, P. W. Burridge

This paper identifies a transcription factor combination (MST) that successfully reprograms human fibroblasts into cardiomyocyte-like cells with spontaneous contraction and gene expression profiles similar to cardiomyocytes.

bioRxiv · Mar 14, 2023Cell Biology

Recombinant annexin A6 promotes membrane repair in a stem cell derived-cardiomyocyte model of dystrophic cardiomyopathy

D. E. Fullenkamp, A. B. Willis, J. L. Curtin, A. P. Amaral, S. I. Harris, P. W. Burridge, A. R. Demonbreun, E. M. McNally

The paper demonstrates that recombinant annexin A6 reduces membrane damage in DMD iPSC-CMs under mechanical stress, showing potential therapeutic efficacy for DMD-related cardiomyopathy.

bioRxiv · Mar 9, 2022 · PreprintBioengineering

GS-967 and Eleclazine Block Sodium Channels in Human Induced Pluripotent Stem Cell-derived Cardiomyocytes

F. Potet, D. E. Egecioglu, P. W. Burridge, A. L. George

This paper investigates the molecular pharmacology of GS-967 and eleclazine on sodium channels in hiPSC-derived cardiomyocytes, finding they exhibit potent use-dependent block and unique effects on slow inactivation.

bioRxiv · May 8, 2020Pharmacology & Toxicology

Negligible-Cost and Weekend-Free Chemically Defined Human iPSC Culture

H.-H. Kuo, X. Gao, J.-M. DeKeyser, K. A. Fetterman, E. A. Pinheiro, C. J. Weddle, H. Fonoudi, M. V. Orman, M. Romero-Tejeda, M. Jouni, M. Blancard, T. Magdy, C. Epting, A. L. George, P. W. Burridge

This paper introduces a cost-effective, open-source hiPSC culture medium (B8) that reduces costs by 97% and allows weekend-free feeding without compromising growth or differentiation.

bioRxiv · Sep 6, 2019Cell Biology