The RNA helicase DDX1 associates with the nuclear RNA exosome and modulates R-loops
J. L. de Amorim, S. W. Leung, R. Haji-Seyed-Javadi, Y. Hou, D. S. Yu, H. Ghalei, S. Khoshnevis, B. Yao, A. H. Corbett
The paper identifies DDX1 as an interactor of the RNA exosome subunit EXOSC3 and shows that their interaction is reduced during DNA damage, affecting R-loop levels in neuronal cells.
bioRxiv · Apr 17, 2023 · PreprintBiochemistry