Human trophoblast stem cells can be used to model placental susceptibility to Toxoplasma gondii and highlight the critical importance of the trophoblast cell surface in pathogen resistance
R. J. da Silva, L. F. Cabo, J. L. George, L. A. Cahoon, L. Yang, C. B. Coyne, J. P. Boyle
This study uses human trophoblast stem cells to model placental resistance to Toxoplasma gondii and Listeria monocytogenes, showing that syncytiotrophoblasts are more resistant than cytotrophoblasts.
bioRxiv · Nov 10, 2023 · PreprintMicrobiology