Author

J. L. Hornick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Organism:mouse· 1

Frequent Co-Authors

A. L. Damon· 1 shared A. Rotem· 1 shared B. A. Van Tine· 1 shared B. M. Titchen· 1 shared B. N. Tomson· 1 shared B. S. Thomas· 1 shared C. A. Painter· 1 shared C. Mackichan· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. L. Damon

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Author profile →

3 papers

Recent·Most cited

Intertumoral lineage diversity and immunosuppressive transcriptional programs in well-differentiated gastroenteropancreatic neuroendocrine tumors

S. E. Hoffman, T. W. Dowrey, C. V. Martin, K. Bi, B. M. Titchen, S. Johri, L. DelloStritto, M. Patel, C. Mackichan, S. Inga, J. Chen, G. Grimaldi, S. Napolitano, I. Wakiro, J. Wu, , G. J. Murphy

This study analyzes single-cell transcriptomes of gastroenteropancreatic neuroendocrine tumors to identify lineage diversity and immunosuppressive programs in tumor and immune cells.

bioRxiv · Nov 8, 2022Cancer Biology

Aberrant cell state plasticity mediated by developmental reprogramming precedescolorectal cancer initiation

P. Bala, J. P. Rennhack, D. Aitymbayev, C. X. Morris, S. M. Moyer, G. N. Duronio, P. Doan, z. Li, X. Liang, J. L. Hornick, M. B. Yurgelun, W. Hahn, N. S. Sethi

The paper shows that aberrant cell state plasticity, driven by regenerative activity and developmental reprogramming, occurs before colorectal cancer initiation in mouse models and human patients.

bioRxiv · Sep 22, 2022Cancer Biology

The Angiosarcoma Project: enabling genomic and clinical discoveries in a rare cancer through patient-partnered research

C. A. Painter, E. Jain, B. N. Tomson, M. Dunphy, R. E. Stoddard, B. S. Thomas, A. L. Damon, S. Shah, D. Kim, J. Gomez Tejeda Zanudo, J. L. Hornick, Y.-L. Chen, P. Merriam, C. P. Raut, G. D. Demetri, , N. Wagle

The paper describes the Angiosarcoma Project, a patient-partnered initiative that generates genomic data on angiosarcoma, identifying recurrent mutations and potential therapeutic targets.

bioRxiv · Aug 26, 2019Cancer Biology