Author

J. L. Mendenhall

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Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Assay:proteomics· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

A. G. McKee· 1 shared C. P. Kuntz· 1 shared H. Woods· 1 shared J. Meiler· 1 shared J. P. Schlebach· 1 shared N. B. Zelt· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiophysics

A. G. McKee

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1 paper

Recent·Most cited

Towards Generalizable Predictions for the Effects of Mutations on G-Protein Coupled Receptor Expression

C. P. Kuntz, H. Woods, A. G. McKee, N. B. Zelt, J. L. Mendenhall, J. Meiler, J. P. Schlebach

This paper trains neural networks to predict how mutations affect plasma membrane expression of GPCRs, showing structural features alone can generalize across related proteins.

bioRxiv · Dec 28, 2021Biophysics