Author

N. B. Zelt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:proteomics· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

C. P. Kuntz· 2 shared J. P. Schlebach· 2 shared A. G. McKee· 1 shared B. J. Bender· 1 shared H. Woods· 1 shared J. J. Ziarek· 1 shared J. L. Mendenhall· 1 shared J. Meiler· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

C. P. Kuntz

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Towards Generalizable Predictions for the Effects of Mutations on G-Protein Coupled Receptor Expression

C. P. Kuntz, H. Woods, A. G. McKee, N. B. Zelt, J. L. Mendenhall, J. Meiler, J. P. Schlebach

This paper trains neural networks to predict how mutations affect plasma membrane expression of GPCRs, showing structural features alone can generalize across related proteins.

bioRxiv · Dec 28, 2021Biophysics

Molecular Basis for the Evolved Instability of a Human G-Protein Coupled Receptor

L. M. Chamness, N. B. Zelt, C. P. Kuntz, B. J. Bender, W. D. Penn, J. J. Ziarek, J. P. Meiler, J. P. Schlebach

The paper identifies a C-terminal truncation and increased TM domain polarity in GnRHR as evolutionary adaptations that reduce receptor stability and activity.

bioRxiv · Dec 20, 2019Biochemistry