Effectiveness and selectivity of a heroin conjugate vaccine to attenuate heroin, 6-acetylmorphine, and morphine antinociception in rats: Comparison with naltrexone
K. L. Schwienteck, S. Blake, P. T. Bremer, J. L. Poklis, E. A. Townsend, S. S. Negus, M. L. Banks
This study evaluates a heroin conjugate vaccine's effectiveness in reducing heroin, 6-AM, and morphine antinociception in rats, finding it less effective but more selective than naltrexone.
bioRxiv · Jun 4, 2019Pharmacology & Toxicology