Author

S. S. Negus

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 5

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:rat· 5 Assay:behavioral assay· 3 Research Focus:cell signaling & trafficking· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

E. A. Townsend· 2 shared L. Karim-Nejad· 2 shared L. P. Legakis· 2 shared M. L. Banks· 2 shared C. M. Diester· 1 shared D. E. Selley· 1 shared D. N. Potter· 1 shared E. H. Chartoff· 1 shared

Activity by Year

2019-2022 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersPharmacology & Toxicology

E. A. Townsend

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5 papers

Recent·Most cited

Effects of environmental manipulations on cocaine-vs-social choice in male and female rats

M. M. Marcus, M. L. Banks, S. S. Negus

This study examines how environmental manipulations affect cocaine vs. social choice in rats, finding that reinforcer magnitude and non-contingent presentations do not significantly alter choice behavior.

Pharmacology Biochemistry and Behavior · Oct 1, 2022Peer-reviewedPharmacology & Toxicology

Effects of Repeated Treatment with Monoamine-Transporter-Inhibitor Antidepressants on Pain-Related Depression of Intracranial Self-Stimulation in Rats

S. S. Negus, L. Karim-Nejad, L. P. Legakis

This study examines the effects of repeated treatment with monoamine transporter inhibitors on pain-related depression in rats, finding that bupropion effectively blocks depression and weight loss, while other inhibitors show delayed antinociceptive effects.

bioRxiv · Sep 4, 2019Pharmacology & Toxicology

Attenuated Dopamine Receptor Signaling in Nucleus Accumbens Core in a Rat Model of Chemically-Induced Neuropathy

D. E. Selley, M. F. Lazenka, L. J. Sim-Selley, D. N. Potter, E. H. Chartoff, W. A. Carlezon, S. S. Negus

This study shows that chemically-induced neuropathy in rats reduces specific dopamine receptor signaling in the nucleus accumbens core.

bioRxiv · Aug 2, 2019Pharmacology & Toxicology

Comparison of Chemotherapy Effects on Mechanical Sensitivity and Food-Maintained Operant Responding in Male and Female Rats

L. P. Legakis, C. M. Diester, E. A. Townsend, L. Karim-Nejad, S. S. Negus

This study compares the effects of four chemotherapies on mechanical sensitivity and operant responding in rats, finding sustained hypersensitivity but no consistent behavioral depression.

bioRxiv · Jul 22, 2019Pharmacology & Toxicology

Effectiveness and selectivity of a heroin conjugate vaccine to attenuate heroin, 6-acetylmorphine, and morphine antinociception in rats: Comparison with naltrexone

K. L. Schwienteck, S. Blake, P. T. Bremer, J. L. Poklis, E. A. Townsend, S. S. Negus, M. L. Banks

This study evaluates a heroin conjugate vaccine's effectiveness in reducing heroin, 6-AM, and morphine antinociception in rats, finding it less effective but more selective than naltrexone.

bioRxiv · Jun 4, 2019Pharmacology & Toxicology