Absence of SIV-specific CD8+ T cells in germinal centers may set the stage for persistent infection
S. Li, J. M. Folkvord, K. J. Kovacs, R. K. Wagstaff, G. Mwakalundwa, A. K. Rendahl, E. G. Rakasz, E. Connick, P. J. Skinner
The paper shows that SIV-specific CD8+ T cells are excluded from germinal centers early in infection, potentially contributing to persistent viral infection.
bioRxiv · Sep 3, 2018Immunology