Expansion of Functional Regulatory T Cells Using Soluble RAGE Prevents Type 1 Diabetes
S. Leung, D. J. Borg, D. A. McCarthy, T. Boursalian, J. Cracraft, A. Zhuang, A. Fotheringham, N. Flemming, T. Watkins, J. Miles, P.-H. Groop, J. Scheijen, C. Schalkwijk, R. Steptoe, K. Radford, , J. M. Forbes
This study shows that soluble RAGE (sRAGE) expands functional regulatory T cells and prevents type 1 diabetes in mice and human T cells.
bioRxiv · Jan 10, 2020Immunology