Author

J. M. Heather

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. N. Hata· 1 shared B. Chain· 1 shared B. Gerritsen· 1 shared D. G. Millar· 1 shared D. S. Johnson· 1 shared M. Cobbold· 1 shared M. Herrero Alonso· 1 shared M. Ismail· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. N. Hata

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Author profile →

2 papers

Recent·Most cited

Stitchr: stitching coding TCR nucleotide sequences from V/J/CDR3 information

J. M. Heather, M. J. Spindler, M. Herrero Alonso, Y. I. Shui, D. G. Millar, D. S. Johnson, M. Cobbold, A. N. Hata

Stitchr generates full-length coding TCR sequences from V/J/CDR3 information, validated through synthesis and transduction in Jurkat cells, enabling efficient TCR engineering and analysis.

bioRxiv · Dec 20, 2021Immunology

The naive T-cell receptor repertoire has an extremely broad distribution of clone sizes

P. C. de Greef, T. Oakes, B. Gerritsen, M. Ismail, J. M. Heather, R. Hermsen, B. Chain, R. J. de Boer

The paper estimates the distribution of clone sizes in the human naive T-cell receptor repertoire and finds that while most clones are small, some large clones exist due to peripheral selection.

bioRxiv · Jul 3, 2019Immunology