Author

J. M. Issa

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

A. C. Monteleone-Cassiano· 1 shared A. F. Assis· 1 shared D. Pitol· 1 shared E. A. Donadi· 1 shared G. A. Passos· 1 shared J. A. Dernowsek· 1 shared R. S. Mascarenhas· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. C. Monteleone-Cassiano

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1 paper

Recent·Most cited

The absence of the autoimmune regulator gene (AIRE) impairs the three-dimensional structure of medullary thymic epithelial cell spheroids

A. C. Monteleone-Cassiano, J. A. Dernowsek, R. S. Mascarenhas, A. F. Assis, D. Pitol, J. M. Issa, E. A. Donadi, G. A. Passos

This study shows that AIRE deficiency disrupts mTEC spheroid 3D structure and alters adhesion gene regulation.

bioRxiv · Aug 11, 2021Immunology