Author

J. M. Xavier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Assay:DNA methylation· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A.-T. Maia· 3 shared R. Magno· 3 shared A. Bosma· 1 shared A. C. Jacinta-Fernandes· 1 shared A. Marreiros· 1 shared A. V. LEE· 1 shared B. P. de Almeida· 1 shared C. Caldas· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersCancer Biology

A.-T. Maia

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Estrogen regulation and functional role of FGFR4 in estrogen receptor positive breast cancer

K. Ding, L. Chen, K. M. Levine, M. J. Sikora, N. Tasdemir, D. Dabbs, R. Jankowitz, R. S. Hazan, O. S. Shah, J. M. Xavier, A. V. LEE, S. Oesterreich

This study investigates FGFR4's role in endocrine resistance in ER+ breast cancer and finds it does not generally mediate resistance, though HER2-like subtypes may respond to FGFR4 inhibition.

bioRxiv · Mar 18, 2024 · PreprintCancer Biology

Allelic expression imbalance of PIK3CA mutations is frequent in breast cancer and prognostically significant

L. W. Correia, J. M. Xavier, R. Magno, B. P. de Almeida, F. Esteves, I. Duarte, M. Eldridge, C. Sun, A. Bosma, L. Mittempergher, A. Marreiros, R. Bernards, C. Caldas, S.-F. Chin, A.-T. Maia

The paper identifies frequent allelic expression imbalance of PIK3CA mutations in breast cancer and links it to poor prognosis.

bioRxiv · Mar 5, 2021Cancer Biology

Allele-specific miRNA-binding analysis identifies candidate target genes for breast cancer risk

A. C. Jacinta-Fernandes, J. M. Xavier, R. Magno, J. Lage, A.-T. Maia

The paper analyzes allele-specific miRNA-binding to identify candidate target genes for breast cancer risk using GWAS variants and miRNA-binding prediction tools.

bioRxiv · Sep 20, 2019Cancer Biology

Alternative splicing regulation by GWAS risk loci for breast cancer

J. Machado, R. Magno, J. M. Xavier, A.-T. Maia

This study identifies breast cancer risk SNPs associated with alternative splicing in normal breast tissue, highlighting the role of splicing regulation in cancer susceptibility.

bioRxiv · Sep 12, 2019 · PreprintCancer Biology