Author

J. Madariaga-Marcos

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Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

D. J. Kauert· 1 shared F. E. Kemmerich· 1 shared I. Songailiene· 1 shared M. Rutkauskas· 1 shared P. Aldag· 1 shared R. Seidel· 1 shared T. Sinkunas· 1 shared V. Siksnys· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiophysics

D. J. Kauert

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1 paper

Recent·Most cited

Dynamic interplay between target search and recognition for the Cascade surveillance complex of type I-E CRISPR-Cas systems

P. Aldag, M. Rutkauskas, J. Madariaga-Marcos, I. Songailiene, T. Sinkunas, F. E. Kemmerich, D. J. Kauert, V. Siksnys, R. Seidel

This study investigates how the Type I-E CRISPR-Cas Cascade complex searches and recognizes DNA targets, showing that recognition probabilities are low and increased by DNA supercoiling and limited 1D diffusion.

bioRxiv · Dec 18, 2022Biophysics