Author

P. Aldag

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Assay:DNA methylation· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

M. Rutkauskas· 2 shared R. Seidel· 2 shared A. Schmidbauer· 1 shared D. Grohmann· 1 shared D. J. Kauert· 1 shared F. E. Kemmerich· 1 shared F. Fettes· 1 shared F. Welzel· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

M. Rutkauskas

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Dynamic interplay between target search and recognition for the Cascade surveillance complex of type I-E CRISPR-Cas systems

P. Aldag, M. Rutkauskas, J. Madariaga-Marcos, I. Songailiene, T. Sinkunas, F. E. Kemmerich, D. J. Kauert, V. Siksnys, R. Seidel

This study investigates how the Type I-E CRISPR-Cas Cascade complex searches and recognizes DNA targets, showing that recognition probabilities are low and increased by DNA supercoiling and limited 1D diffusion.

bioRxiv · Dec 18, 2022Biophysics

Probing the stability of the SpCas9-DNA complex after cleavage

P. Aldag, F. Welzel, L. Jakob, A. Schmidbauer, M. Rutkauskas, F. Fettes, D. Grohmann, R. Seidel

This study investigates the stability of SpCas9-DNA complexes after cleavage using single-molecule magnetic tweezers, finding that post-cleavage states are more stable than pre-cleavage states.

bioRxiv · Aug 4, 2021Biophysics