Author

J. Manuel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:snRNA-seq· 2 Assay:spatial transcriptomics· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

C. Thoeni· 2 shared E. Winter· 2 shared G. D. Bader· 2 shared I. D. McGilvray· 2 shared S. A. MacParland· 2 shared S. Chung· 2 shared T. S. Andrews· 2 shared A. Gehring· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

C. Thoeni

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Single-cell and spatial transcriptomics reveals the human liver immunological landscape and myeloid dysfunction in PSC.

T. S. Andrews, D. Nakib, C. Perciani, X. Z. Ma, L. Liu, E. Winter, D. Camat, S. Chung, J. Manuel, S. Mangroo, B. Hansen, B. Arpinder, C. Thoeni, B. Sayed, J. Feld, , S. A. MacParland

This paper uses single-cell and spatial transcriptomics to map the immune landscape of PSC livers, revealing myeloid dysfunction and cytokine-driven inflammation.

bioRxiv · Jul 28, 2023 · PreprintCell Biology

The ecological consequences and evolution of retron-mediated suicide as a way to protect Escherichia coli from being killed by phage

B. A. Berryhill, R. Garcia, J. Manuel, B. R. Levin

The paper models and experiments show retron-mediated abortive infection protects E. coli from phage but only under specific conditions.

bioRxiv · May 5, 2021Evolutionary Biology

Single Cell, Single Nucleus and Spatial RNA Sequencing of the Human Liver Identifies Hepatic Stellate Cell and Cholangiocyte Heterogeneity

T. S. Andrews, J. Atif, J. C. Liu, C. T. Perciani, X.-Z. Ma, C. Thoeni, M. Slyper, G. Eraslan, A. Segerstolpe, J. Manuel, S. Chung, E. Winter, I. Cirlan, N. Khuu, S. Fischer, , S. A. MacParland

This study uses scRNA-seq and snRNA-seq to analyze 73,295 human liver cells, revealing heterogeneity in hepatic stellate cells, cholangiocytes, and interzonal hepatocytes.

bioRxiv · Mar 27, 2021Cell Biology