Author

A. Segerstolpe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

M. Slyper· 3 shared A. Regev· 2 shared A. Rotem· 2 shared I. Wakiro· 2 shared J. Jane-Valbuena· 2 shared O. Ashenberg· 2 shared O. Rozenblatt-Rosen· 2 shared S. Vigneau· 2 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersCancer Biology

M. Slyper

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Author profile →

3 papers

Recent·Most cited

A spatial cell atlas of neuroblastoma reveals developmental, epigenetic and spatial axis of tumor heterogeneity

A. G. Patel, O. Ashenberg, N. B. Collins, A. Segerstolpe, S. Jiang, M. Slyper, X. Huang, C. Caraccio, H. Jin, H. Sheppard, K. Xu, T.-C. Chang, B. A. Orr, A. Shirinifard, R. H. Chapple, , S. J. Rodig

This paper creates a spatial cell atlas of neuroblastoma, revealing tumor heterogeneity through multi-omics data and identifying spatial compartmentalization and signaling patterns.

bioRxiv · Jan 7, 2024 · PreprintCancer Biology

A cellular and spatial atlas of TP53-associated tissue remodeling in lung adenocarcinoma

W. Zhao, B. Kepecs, N. R. Mahadevan, A. Segerstolpe, J. L. Weirather, N. R. Besson, B. Giotti, B. Y. Soong, C. Li, S. Vigneau, M. Slyper, I. Wakiro, J. Jane-Valbuena, O. Ashenberg, A. Rotem, , A. M. Tsankov

This study constructs a multi-omic atlas of TP53-mutant lung adenocarcinoma tumors, revealing altered cellular identity, gene expression programs, and spatial interactions in the tumor microenvironment.

bioRxiv · Jun 28, 2023 · PreprintCancer Biology

Single Cell, Single Nucleus and Spatial RNA Sequencing of the Human Liver Identifies Hepatic Stellate Cell and Cholangiocyte Heterogeneity

T. S. Andrews, J. Atif, J. C. Liu, C. T. Perciani, X.-Z. Ma, C. Thoeni, M. Slyper, G. Eraslan, A. Segerstolpe, J. Manuel, S. Chung, E. Winter, I. Cirlan, N. Khuu, S. Fischer, , S. A. MacParland

This study uses scRNA-seq and snRNA-seq to analyze 73,295 human liver cells, revealing heterogeneity in hepatic stellate cells, cholangiocytes, and interzonal hepatocytes.

bioRxiv · Mar 27, 2021Cell Biology