Author

I. Cirlan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Regev· 1 shared A. Segerstolpe· 1 shared C. T. Perciani· 1 shared C. Thoeni· 1 shared D. Cescon· 1 shared E. Winter· 1 shared G. D. Bader· 1 shared G. Eraslan· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

A. Regev

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Non-coding mutations reveal cancer driver cistromes in luminal breast cancer

S. El Ghamrasni, R. Quevedo, J. R. Hawley, P. Mazrooei, Y. Hanna, I. Cirlan, H. Zhu, J. P. Bruce, L. E. Oldfield, S. Y. C. Yang, P. Guilhamon, J. Reimand, D. Cescon, S. J. Done, M. Lupien, T. Pugh

The paper identifies cancer driver cistromes in luminal breast cancer by analyzing non-coding mutations in cis-regulatory elements from ATAC-seq data and integrating them with somatic mutations.

bioRxiv · May 29, 2021Cancer Biology

Single Cell, Single Nucleus and Spatial RNA Sequencing of the Human Liver Identifies Hepatic Stellate Cell and Cholangiocyte Heterogeneity

T. S. Andrews, J. Atif, J. C. Liu, C. T. Perciani, X.-Z. Ma, C. Thoeni, M. Slyper, G. Eraslan, A. Segerstolpe, J. Manuel, S. Chung, E. Winter, I. Cirlan, N. Khuu, S. Fischer, , S. A. MacParland

This study uses scRNA-seq and snRNA-seq to analyze 73,295 human liver cells, revealing heterogeneity in hepatic stellate cells, cholangiocytes, and interzonal hepatocytes.

bioRxiv · Mar 27, 2021Cell Biology