Cell BiologybioRxiv
The Heterochromatin protein 1 is a master regulator in RNA splicing precision deficient in ulcerative colitis
J. Mata -Garrido, Y. Xiang, Y. Chang-Marchand…·L. Arbibe
This study identifies HP1γ as a regulator of RNA splicing in the gut, showing its deficiency leads to splicing errors and progerin production, linking it to ulcerative colitis and aging diseases.