Author

J. Muhle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Assay:structural biology· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

C.-J. Tsai· 2 shared O. Tejero· 2 shared A. D. Diethelm· 1 shared A. Furrer· 1 shared A. Terakita· 1 shared A. Wach· 1 shared C. Bacellar· 1 shared C. Cirelli· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersBiochemistry

C.-J. Tsai

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2 papers

Recent·Most cited

Activating an invertebrate bistable opsin with the all-trans 6.11 retinal analogue

M. J. Rodrigues, O. Tejero, J. Muhle, F. K. Pamula, I. Das, C.-J. Tsai, A. Terakita, M. Sheves, G. F. X. Schertler

This study shows that the all-trans 6.11 retinal analogue activates the invertebrate bistable opsin JSR1 and enables complex formation with downstream signaling partners.

bioRxiv · Apr 8, 2024 · PreprintBiochemistry

ULTRAFAST STRUCTURAL CHANGES DIRECT THE FIRST MOLECULAR EVENTS OF VISION

T. Gruhl, T. Weinert, M. Rodrigues, C. J. Milne, G. Ortolani, K. Nass, E. Nango, S. Sen, P. J. Johnson, C. Cirelli, A. Furrer, S. Mous, P. Skopintsev, D. James, F. Dworkowski, , Scher

This study uses ultrafast crystallography to reveal how photoactivated retinal initiates structural changes in rhodopsin, leading to GPCR activation and vision.

bioRxiv · Oct 14, 2022 · PreprintBiochemistry