Author

A. Terakita

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4 Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:proteomics· 3 Organism:mouse· 2 Research Focus:protein folding & dynamics· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1

Frequent Co-Authors

M. Koyanagi· 5 shared C.-J. Tsai· 2 shared F. K. Pamula· 2 shared G. F. X. Schertler· 2 shared I. Das· 2 shared M. J. Rodrigues· 2 shared M. Sheves· 2 shared O. Tejero· 2 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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5 shared papersBiochemistry

M. Koyanagi

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Active state structures of a bistable visual opsin bound to G proteins

O. Tejero, F. K. Pamula, M. Koyanagi, T. Nagata, P. Afanasyev, I. Das, X. Deupi, M. Sheves, A. Terakita, G. F. X. Schertler, M. J. Rodrigues, C.-J. Tsai

This study presents active state structures of a bistable opsin, JSR1, bound to G proteins, revealing differences in activation mechanisms between monostable and bistable opsins.

bioRxiv · Apr 9, 2024Biochemistry

Activating an invertebrate bistable opsin with the all-trans 6.11 retinal analogue

M. J. Rodrigues, O. Tejero, J. Muhle, F. K. Pamula, I. Das, C.-J. Tsai, A. Terakita, M. Sheves, G. F. X. Schertler

This study shows that the all-trans 6.11 retinal analogue activates the invertebrate bistable opsin JSR1 and enables complex formation with downstream signaling partners.

bioRxiv · Apr 8, 2024 · PreprintBiochemistry

Engineered blue-shifted melanopsins for subcellular optogenetics

D. Wijayaratna, F. Sacchetta, L. Pedraza Gonzalez, F. Fanelli, T. Sugihara, M. Koyanagi, S. Piyawardana, K. Ghotra, W. Thotamune, A. Terakita, M. Olivucci, A. Karunarathne

This paper engineers blue-shifted melanopsin mutants using computational methods to enable subcellular optogenetic control without red light activation.

bioRxiv · Oct 7, 2023 · PreprintBiochemistry

High-performance GPCR optogenetics based on molecular properties of animal opsins, MosOpn3 and LamPP

M. Koyanagi, B. Shen, T. Nagata, L. Sun, S. Wada, S. Kamimura, E. Kage-Nakadai, A. Terakita

This study evaluates two animal opsins, MosOpn3 and LamPP, for GPCR optogenetics in C. elegans, showing high sensitivity and color-dependent behavioral control.

bioRxiv · Feb 7, 2022 · PreprintBiochemistry

The Emergence of the Metabolic Signaling of the Nucleoredoxin-like Genes during Evolution

N. Ait-Ali, F. Blond, E. Clerin, A. Morshedian, Q. Cesar, F. Delalande, M. Koyanagi, C. Birck, J. Han, X. Ren, A. Dorsselaer, A. Terakita, G. Fain, T. Leveillard

The paper traces the evolutionary emergence of metabolic signaling via nucleoredoxin-like genes, showing their role in photoreceptor communication and glucose regulation across species.

bioRxiv · Jan 6, 2022 · PreprintEvolutionary Biology

Whale shark rhodopsin adapted to its vertically wide-ranging lifestyle

K. Yamaguchi, M. Koyanagi, K. Sato, A. Terakita, S. Kuraku

This study identifies two amino acid sites in whale shark rhodopsin that contribute to its blue shift and thermal stability, enabling its wide vertical range.

bioRxiv · Oct 1, 2021 · PreprintEvolutionary Biology