Cholesterol in the cargo membrane reduces kinesin-1 binding to microtubules in the presence of tau
Q. Li, J. T. Ferrare, J. Silver, J. O. Wilson, L. Arteaga-Castaneda, W. Qiu, M. Vershinin, S. J. King, K. C. Neuman, J. Xu
The paper investigates how cholesterol in a cargo membrane affects kinesin-1 binding to microtubules in the presence of tau, showing that cholesterol enhances tau's inhibitory effect.
bioRxiv · Mar 1, 2022Biophysics