Inhibition of CD40-TRAF6 signaling protects against aneurysm development and progression
M. Ommer-Blaesius, T. Vajen, C. Elster, S. Verheyen, S. Pfeiler, C. Quast, J. Odendahl, A. Lang, E. Lutgens, M. Kelm, N. Gerdes
This study shows that inhibiting CD40-TRAF6 signaling reduces abdominal aortic aneurysm severity and progression in mice.
bioRxiv · Mar 24, 2023 · PreprintPharmacology & Toxicology