J. Oteo-Iglesias

This study investigates how cinnamaldehyde inhibits quorum sensing in K. pneumoniae to reduce phage resistance by proteomic analysis and infection assays.

This study shows that mucin promotes phage resistance in K. pneumoniae, but mucolytic agents like NAC reduce this resistance, suggesting their potential use in phage therapy.

This study evaluates the in vitro and in vivo synergy between lytic phages and octapeptin OPX10053 against K. pneumoniae clinical isolates, showing synergistic activity but toxicity concerns with OPX10053.

The paper analyzes molecular defense mechanisms in phages and Klebsiella pneumoniae through proteomic and genomic studies, revealing interactions such as CRISPR-Cas systems and toxin-antitoxin systems.

This study examines how the second dose of the BNT162b2 vaccine affects T cell immunity in naive and previously infected individuals, finding reduced cellular immunity in recovered individuals.

This study evaluates the in vitro and in vivo efficacy of combining colistin with endolysins ElyA1 and ElyA2 against MDR pathogens, finding that ElyA1 enhances colistin's antimicrobial activity and reduces its MIC.