Author

A. Barrio-Pujante

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:bacteria (other)· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

C. Ortiz-Cartagena· 4 shared F. Fernandez-Cuenca· 4 shared I. Bleriot· 4 shared J. Oteo-Iglesias· 4 shared L. Blasco· 4 shared L. Fernandez-Garcia· 4 shared M. Tomas· 4 shared O. Pacios· 4 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersMicrobiology

C. Ortiz-Cartagena

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Control of the phage defence mechanisms by Quorum sensing (QS) in clinical isolates of Klebsiella pneumoniae

A. Barrio-Pujante, I. Bleriot, L. Blasco, L. Fernandez-Garcia, O. Pacios, C. Ortiz-Cartagena, M. Lopez, F. Fernandez-Cuenca, J. Oteo-Iglesias, M. Tomas

This study investigates how cinnamaldehyde inhibits quorum sensing in K. pneumoniae to reduce phage resistance by proteomic analysis and infection assays.

bioRxiv · Dec 5, 2023 · PreprintMicrobiology

Molecular Studies of Phages-Klebsiella pneumoniae in a Mucoid Environment: Innovative use of mucolytic agents prior to the administration of lytic phages

O. Pacios, L. Blasco, C. Ortiz-Cartagena, I. Bleriot, L. Fernandez-Garcia, M. Lopez, A. Barrio-Pujante, A. Pascual, F. Fernandez-Cuenca, L. Martinez-Martinez, B. Aracil, J. Oteo-Iglesias, M. Tomas

This study shows that mucin promotes phage resistance in K. pneumoniae, but mucolytic agents like NAC reduce this resistance, suggesting their potential use in phage therapy.

bioRxiv · Aug 2, 2023 · PreprintMicrobiology

In vitro and in vivo combination of lytic phages and octapeptin OPX10053 against B-lactamase-producing clinical isolates of Klebsiella pneumoniae

O. Pacios, L. Blasco, I. Bleriot, L. Fernandez-Garcia, M. Lopez-Diaz, C. Ortiz-Cartagena, A. Barrio-Pujante, F. Fernandez-Cuenca, B. Aracil, J. Oteo-Iglesias, K. A. Hansford, M. Tomas

This study evaluates the in vitro and in vivo synergy between lytic phages and octapeptin OPX10053 against K. pneumoniae clinical isolates, showing synergistic activity but toxicity concerns with OPX10053.

bioRxiv · Mar 15, 2023 · PreprintMicrobiology

Molecular analysis of the interactions between phages and the bacterial host Klebsiella pneumoniae

I. Bleriot, L. Blasco, O. Pacios, L. Fernandez-Garcia, M. Lopez, C. Ortiz-Cartagena, A. Barrio-Pujante, F. Fernandez-Cuenca, A. Pascual, L. Martinez-Martinez, J. Oteo-Iglesias, M. Tomas

The paper analyzes molecular defense mechanisms in phages and Klebsiella pneumoniae through proteomic and genomic studies, revealing interactions such as CRISPR-Cas systems and toxin-antitoxin systems.

bioRxiv · Sep 12, 2022 · PreprintMicrobiology