Author

J. P. Adams

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. R. Hoover· 1 shared A. R. Naqash· 1 shared C. Furrer· 1 shared J. A. Littlechild· 1 shared J. F. Papin· 1 shared K. Liu· 1 shared M. Zhao· 1 shared N. Harmer· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

A. R. Hoover

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2 papers

Recent·Most cited

Single-cell transcriptomics reveals that tumor-infiltrating natural killer cells are activated by localized ablative immunotherapy and share anti-tumor signatures induced by immune checkpoint inhibitors

K. Liu, N. Sadeghipour, A. R. Hoover, T. I. Valerio, C. Furrer, J. P. Adams, A. R. Naqash, M. Zhao, J. F. Papin, W. R. Chen

This study shows that localized ablative immunotherapy activates NK cells and shares anti-tumor gene signatures with immune checkpoint inhibitors, correlating with improved patient survival.

bioRxiv · May 2, 2023 · PreprintImmunology

Engineering a seven enzyme biotransformation using mathematical modelling and characterized enzyme parts

W. Finnigan, R. Cutlan, R. Snajdrova, J. P. Adams, J. A. Littlechild, N. Harmer

The paper models and optimizes a seven-enzyme, three-step biotransformation using a deterministic process model and genetic algorithm, validated experimentally to show reliable optimization of complex enzyme cascades.

bioRxiv · Apr 9, 2019Biochemistry