Author

J. Planas-Iglesias

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Assay:multiome· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Kunka· 1 shared A. Legrand· 1 shared C. Harms· 1 shared D. Bednar· 1 shared D. Wright· 1 shared J. Damborsky· 1 shared J. Klein-Seetharaman· 1 shared J. Sedlar· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiophysics

A. Kunka

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2 papers

Recent·Most cited

CoVAMPnet: Comparative Markov State Analysis for Studying Effects of Drug Candidates on Disordered Biomolecules

S. M. Marques, P. Kouba, A. Legrand, J. Sedlar, L. Disson, J. Planas-Iglesias, Z. Sanusi, A. Kunka, J. Damborsky, T. Pajdla, Z. Prokop, S. Mazurenko, J. Sivic, D. Bednar

This paper introduces CoVAMPnet, a framework to analyze how drug candidates affect disordered biomolecules, finding that TMP and SPA preserve structured conformations of Aβ42.

bioRxiv · Jan 6, 2023Biophysics

Inter-domain dynamics and fibrinolytic activity of matrix metalloprotease-1

L. Kumar, J. Planas-Iglesias, C. Harms, S. Kamboj, D. Wright, J. Klein-Seetharaman, S. K. Sarkar

This study investigates how inter-domain dynamics of MMP1 correlate with its fibrinolytic activity using single-molecule FRET and kinetic modeling.

bioRxiv · Jul 6, 2020Biophysics