Author

J. R. Castano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

F. Aalam· 2 shared J. Totonchy· 2 shared R. Nabiee· 2 shared N. Alomari· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersMicrobiology

F. Aalam

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintDec 6, 2021

IL-21 signaling promotes the establishment of KSHV infection in human tonsil lymphocytes by increasing early targeting of plasma cells

N. Alomari, F. Aalam, R. Nabiee…·J. Totonchy

The paper shows IL-21 signaling enhances KSHV infection in human tonsil lymphocytes by increasing plasma cell numbers and early infection in these cells.

DOI 10.1101/2021.12.06.471359

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivJan 17, 2020

Analysis of KSHV B lymphocyte lineage tropism in human tonsil reveals efficient infection of CD138+ plasma cells

F. Aalam, R. Nabiee, J. R. Castano, J. Totonchy

This study identifies CD138+ plasma cells as a highly targeted cell type for KSHV infection in human tonsil B lymphocytes, showing variability in susceptibility across donors and host immunological influence.

DOI 10.1371/journal.ppat.1008968

humanbulk RNA-seq

𝕏 PostBluesky