Author

J. R. Hawley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Assay:ATAC-seq· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

M. Lupien· 2 shared C. Arlidge· 1 shared D. Cescon· 1 shared G. Grillo· 1 shared H. Zhu· 1 shared I. Cirlan· 1 shared J. P. Bruce· 1 shared J. Reimand· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

M. Lupien

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2 papers

Recent·Most cited

Cancer BiologybioRxivMay 29, 2021

Non-coding mutations reveal cancer driver cistromes in luminal breast cancer

S. El Ghamrasni, R. Quevedo, J. R. Hawley…·T. Pugh

The paper identifies cancer driver cistromes in luminal breast cancer by analyzing non-coding mutations in cis-regulatory elements from ATAC-seq data and integrating them with somatic mutations.

DOI 10.1158/1541-7786.mcr-21-0471

humanwhole-genome sequencing

𝕏 PostBluesky

Cancer BiologybioRxivJan 5, 2021

Cis-Regulatory Element Hijacking by Structural Variants Overshadows Higher-Order Topological Changes in Primary Prostate Cancer

J. R. Hawley, S. Zhou, C. Arlidge…·M. Lupien

The paper shows that structural variants causing cis-regulatory element hijacking have a greater impact on gene expression than changes in three-dimensional chromatin topology in primary prostate cancer.

DOI 10.1158/0008-5472.can-21-2056

humanChIP-seq

𝕏 PostBluesky