Author

J. R. Randall

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Assay:proteomics· 3 Organism:human· 2 Approach:machine learning (classical)· 2 Organism:bacteria (other)· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:sequence-to-function modeling· 1

Frequent Co-Authors

B. W. Davies· 2 shared C. O. Wilke· 2 shared T. J. Cole· 2 shared A. O'Donnell· 1 shared B. Davies· 1 shared C. D. DuPai· 1 shared G. Davidson· 1 shared J. Garza· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

B. W. Davies

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Deep mutational scanning and machine learning uncover antimicrobial peptide features driving membrane selectivity

J. R. Randall, L. Vieira, C. O. Wilke, B. W. Davies

The paper uses deep mutational scanning and machine learning to identify sequence features in antimicrobial peptides that enhance bacterial membrane selectivity while reducing mammalian toxicity.

bioRxiv · Jul 28, 2023 · PreprintBiochemistry

Adapting antibacterial display to identify serum active macrocyclic peptide antibiotics

J. R. Randall, K. Groover, A. O'Donnell, J. Garza, T. J. Cole, B. Davies

This study identifies new macrocyclic peptide antibiotics active in human serum by screening a library under serum conditions, finding that sequence factors like length, charge, and disulfide bonds influence activity.

bioRxiv · Jul 28, 2023Microbiology

Designing β-hairpin peptide macrocycles for antibiotic potential

J. R. Randall, C. D. DuPai, T. J. Cole, G. Davidson, K. E. Groover, C. O. Wilke, B. W. Davies

The paper designs and screens a synthetic macrocyclic β-hairpin peptide library for antibiotic potential, identifying active peptides with unique structural and charge features.

bioRxiv · Jun 21, 2022 · PreprintBiochemistry