Deep mutational scanning and machine learning uncover antimicrobial peptide features driving membrane selectivity
J. R. Randall, L. Vieira, C. O. Wilke, B. W. Davies
The paper uses deep mutational scanning and machine learning to identify sequence features in antimicrobial peptides that enhance bacterial membrane selectivity while reducing mammalian toxicity.
bioRxiv · Jul 28, 2023 · PreprintBiochemistry